ordered M and just tried on; fits well on my frame.
Honestly, i ordered these because they were 50% off; it was a great deal and worth a try.
6', 185 lbs, athletic build.
i have a 33" waist and a 34" inseam, and a L Hanes undershirt is snug on me.
the legs are right down to my ankles, which fine, as i wear Castelli booties when it's cold. The ankles are loose enough to fit over the booties properly. The seat fits fine, and the chamois seems to be comfortable.
stitching and construction are excellent, like all Gore items that i own.
it bears repeating that these run large, especially if you're used to Euro sizing; i bought a medium.
i wear a 3XL Castelli jacket.