I was looking for a women's saddle with a little padding to replace my too big, too uncomfortable Selle Italia Diva. Although the Diva seems very popular, I rode off-center due to its size. In a chat session to look at other saddles, the rep said the Astute was popular with the women at CC, but it was not padded. I ordered this and four others. Visually, three were discounted and sent back. I tried the Selle Italia lady gel S and immediately discounted it for the hard sit bone area. Overall it was much firmer than the Astute, which has enough but not too much padding. I've ridden the Astute saddle on at least 5 rides now (40-85 miles each). It isn't perfect, but it is quite tolerable. I don't rub my legs on the nose area, and the sit bones are happy. Some soft tissue issues remain, but I think these may be due to old shorts or the saddle and cleat positions, which were just changed at a local store known for its fit assessments.
As a reference, I was measured to have 115 mm sit bone distance, and I'm 5'4", 120 lbs.