Except for a synthetic biocide preservative: methylisothiazolinone. This is a strong allergen and causes contact sensitivity for about 10% of all Americans. This chemical was recently named as allergen of the year by the Contact Dermatitis Society and the Mayo Clinic recently advised people to avoid all consumer products that contain it. It made me very sick for several years until I was diagnosed and treated with cortical steroid injections and a topical steroid 1,000 times stronger than cortisone. I think that my skin will be abnormal for the rest of my life.