That is an open ended question. It depends on your riding style, your maintenance habits, who installs it for you, there are many factors. However, the lighter the chain, the less material holding it together, you do the math. I cleaned my dura-ace chain once a week and relubed with a wax based lubricant. I broke it at 2,000 miles. (on mile 147 of a 150 mile ride) I had it measured just before that ride and my LBS told me that I wasn't even close to needing a new chain. I have a couple hundred miles on a new Ultegra chain and so far so good. If you spin faster, a lighter chain would be OK. If you pedal hard and slow, you may want more steel in your chain. Be sure to do frequent inspections and cleanings. If you want to remove it for easy maintenance, I think the Whipperman is one of the few options left.