The cleats you will want to use with these shoes is determined by the pedals you will be using. If you are using an SPD style then you will want to stick to a 2 hole SPD cleat. If the pedals you are using are a traditional road style cleat then you will want to stick to a 3 hole cleat. These shoes will accommodate both styles.
I would recommend you check the pedals you are using to find out what style pedal you currently are using. A lot of spin classes will use a 2 hole SPD style pedal.